Meta-analysis of interventions to reduce door to needle times in acute ischaemic stroke patients

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Improving Door-to-Needle Times for Acute Ischemic Stroke

Faster treatment with intravenous alteplase (tissue-type plasminogen activator) results in better outcomes. Although the benchmark door-to-needle time (DTN) has been set at 60 minutes, many centers have been able to exceed this benchmark with median times from 20 to 51 minutes. These local efforts have been supported by national and international efforts to reduce DTN time. For example, the Ame...

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Symptom-to-needle Times in Acute Ischemic Stroke and Its Prehospital Related Factors

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Short Door-to-Needle Times in Acute Ischemic Stroke and Prospective Identification of Its Delaying Factors

BACKGROUND The clinical benefit of intravenous thrombolysis (IVT) in acute ischemic stroke is time dependent. Several studies report a short median door-to-needle time (DNT; 20 min), mainly in large tertiary referral hospitals equipped with a level 1 emergency department, a dedicated stroke team available 24/7, and on-site neuroimaging facilities. Meanwhile, in daily practice, the majority of s...

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Simple In-Hospital Interventions to Reduce Door-to-CT Time in Acute Stroke

Background. Intravenous tissue plasminogen activator, a time dependent therapy, can reduce the morbidity and mortality of acute ischemic stroke. This study was designed to assess the effect of simple in-hospital interventions on reducing door-to-CT (DTC) time and reaching door-to-needle (DTN) time of less than 60 minutes. Methods. Before any intervention, DTC time was recorded for 213 patients ...

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Reduction in IV t-PA door to needle times using an Acute Stroke Triage Pathway.

OBJECTIVE To determine the effectiveness of an Acute Stroke Triage Pathway in reducing door to needle times in acute stroke treatment with IV t-PA. BACKGROUND A previous study at our tertiary referral centre, examining IV t-PA door to needle times, was completed in 2000. The median door to needle time was beyond the recommended National Institute for Neurological Disorders and Stroke (NINDS) ...

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ژورنال

عنوان ژورنال: BMJ Open Quality

سال: 2020

ISSN: 2399-6641

DOI: 10.1136/bmjoq-2020-000915